1- HYDOXYBENZOTRIAZOLE ANHYDROUS (HOBT)

1- HYDOXYBENZOTRIAZOLE ANHYDROUS (HOBT) Specification

Medicine Name
1- HYDOXYBENZOTRIAZOLE ANHYDROUS (HOBT)

Chemical Name
1- HYDOXYBENZOTRIAZOLE ANHYDROUS (HOBT)

CAS No
2592-95-2

Type
Pharmaceutical Intermediates

Grade
Industrial Grade

Usage
HOBt extend beyond peptide synthesis to pharmaceutical intermediate manufacturing, combinatorial chemistry, solid-phase synthesis, and fine chemical research, where controlled and efficient amide formation is required.

Purity(%)
99.82 %

Appearance
White to off white powder

Physical Form
Powder

1- HYDOXYBENZOTRIAZOLE ANHYDROUS (HOBT) Trade Information

Minimum Order Quantity
1 Kilograms

Delivery Time
1 Week

About 1- HYDOXYBENZOTRIAZOLE ANHYDROUS (HOBT)

1-Hydroxybenzotriazole anhydrous (HOBt) is a heterocyclic organic compound widely used as a coupling additive in peptide synthesis and other amide-bond-forming reactions. It improves reaction efficiency by suppressing racemization and enhancing coupling yields, especially when used with carbodiimides such as DCC or EDC. HOBt anhydrous is the water-free form, preferred for moisture-sensitive reactions and better reproducibility. Synonyms include 1-Hydroxy-1H-benzotriazole, Hydroxybenzotriazole, HOBt, and HoBt (anhydrous). Applications of HOBt extend beyond peptide synthesis to pharmaceutical intermediate manufacturing, combinatorial chemistry, solid-phase synthesis, and fine chemical research, where controlled and efficient amide formation is required.

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