Methotrexate IP

Methotrexate IP Specification

Solubility
Soluble in alkaline/acidic solutions and organic solvents like DMSO/DMF

Molecular Weight
454.44 GSM (gm/2)

Molecular Formula
C20H22N8O5

Structural Formula
C20H22N8O5

Melting Point
182 C to 205 C

Medicine Name
Methotrexate IP

Chemical Name
Methotrexate IP

CAS No
59-05-2

Type
Pharmaceutical Intermediates

Grade
Other

Usage
Methotrexate is commonly prescribed in the treatment of various cancers such as leukemia, lymphoma, osteosarcoma, and breast cancer, as well as non-oncological conditions including rheumatoid arthritis, psoriasis, and certain inflammatory disorders.

Purity(%)
99.80%

Appearance
A yellow to orange brown, crystalline powder

Physical Form
Powder

Methotrexate IP Trade Information

Minimum Order Quantity
1 Kilograms

Delivery Time
1 Week

About Methotrexate IP

Methotrexate is a folic acid antagonist widely used as an antimetabolite and immunosuppressive agent in oncology and autoimmune therapy. It works by inhibiting the enzyme dihydrofolate reductase, thereby interfering with DNA synthesis, repair, and cellular replication, particularly in rapidly dividing cells. Methotrexate is commonly prescribed in the treatment of various cancers such as leukemia, lymphoma, osteosarcoma, and breast cancer, as well as non-oncological conditions including rheumatoid arthritis, psoriasis, and certain inflammatory disorders. Due to its well-established efficacy and controlled safety profile, methotrexate remains a cornerstone drug in both chemotherapy and chronic immune-mediated disease management. Synonyms: Amethopterin, Methotrexatum, MTX, 4-Amino-10-methylfolic acid.

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