Methotrexate IP Specification
- Solubility
- Soluble in alkaline/acidic solutions and organic solvents like DMSO/DMF
- Structural Formula
- C20H22N8O5
- Melting Point
- 182 C to 205 C
- Molecular Weight
- 454.44 GSM (gm/2)
- Molecular Formula
- C20H22N8O5
- Medicine Name
- Methotrexate IP
- Chemical Name
- Methotrexate IP
- Type
- Pharmaceutical Intermediates
- Usage
- Methotrexate is commonly prescribed in the treatment of various cancers such as leukemia, lymphoma, osteosarcoma, and breast cancer, as well as non-oncological conditions including rheumatoid arthritis, psoriasis, and certain inflammatory disorders.
- Appearance
- A yellow to orange brown, crystalline powder
Methotrexate IP Trade Information
- Minimum Order Quantity
- 1 Kilograms
About Methotrexate IP
Methotrexate is a folic acid antagonist widely used as an antimetabolite and immunosuppressive agent in oncology and autoimmune therapy. It works by inhibiting the enzyme dihydrofolate reductase, thereby interfering with DNA synthesis, repair, and cellular replication, particularly in rapidly dividing cells. Methotrexate is commonly prescribed in the treatment of various cancers such as leukemia, lymphoma, osteosarcoma, and breast cancer, as well as non-oncological conditions including rheumatoid arthritis, psoriasis, and certain inflammatory disorders. Due to its well-established efficacy and controlled safety profile, methotrexate remains a cornerstone drug in both chemotherapy and chronic immune-mediated disease management. Synonyms: Amethopterin, Methotrexatum, MTX, 4-Amino-10-methylfolic acid.