Tetra Butyl Ammonium Fluoride Trihydrate (TBAF) Specification
- Molecular Weight
- 315.51 GSM (gm/2)
- Molecular Formula
- C16H42FNO3
- Medicine Name
- Tetra Butyl Ammonium Fluoride Trihydrate
- Chemical Name
- Tetra Butyl Ammonium Fluoride Trihydrate
- Type
- Pharmaceutical Intermediates
- Usage
- TBAF are most notably in the deprotection of silyl protecting groups (such as TMS, TBDMS, and TIPS) in organic and pharmaceutical synthesis; it is also used in nucleophilic fluorination reactions, phase-transfer catalysis, polymer chemistry, and as a reagent in fine chemical and medicinal chemistry research.
- Appearance
- Brown Crystalline powder
Tetra Butyl Ammonium Fluoride Trihydrate (TBAF) Trade Information
- Minimum Order Quantity
- 1 Kilograms
About Tetra Butyl Ammonium Fluoride Trihydrate (TBAF)
Tetra-n-butylammonium fluoride trihydrate (TBAF3HO) is a quaternary ammonium salt widely used as a convenient and highly effective source of fluoride ions in organic synthesis. It is typically supplied as a hydrated solid or solution and is valued for its strong nucleophilicity and good solubility in polar aprotic solvents. Synonyms include Tetrabutylammonium fluoride trihydrate, n-Tetrabutylammonium fluoride, TBAF trihydrate, and BuNF3HO. Applications of TBAF are most notably in the deprotection of silyl protecting groups (such as TMS, TBDMS, and TIPS) in organic and pharmaceutical synthesis; it is also used in nucleophilic fluorination reactions, phase-transfer catalysis, polymer chemistry, and as a reagent in fine chemical and medicinal chemistry research.