Imatinib Base

Imatinib Base
Imatinib Base
Imatinib Base
Imatinib Base
Imatinib Base
Imatinib Base

Imatinib Base Specification

  • Molecular Formula
  • C29H31N7O
  • Molecular Weight
  • 493.62 GSM (gm/2)
  • Medicine Name
  • Imatinib Base
  • Chemical Name
  • Imatinib Base
  • CAS No
  • 152459-95-5
  • Type
  • Pharmaceutical Intermediates
  • Grade
  • Industrial Grade
  • Usage
  • It is used in oncology for caner treatment like breast and gastointestinal cancer.
  • Purity(%)
  • 99%
  • Appearance
  • Off white powder
  • Physical Form
  • Powder
 

Imatinib Base Trade Information

  • Minimum Order Quantity
  • 1 Kilograms
  • Delivery Time
  • 1 Week
 

About Imatinib Base

Imatinib Base (CAS No. 152459-95-5), also known as Imatinib, CGP57148B, or by its marketed form as the active ingredient in Gleevec (also sold as Glivec), is a selective tyrosine kinase inhibitor widely used in oncology. It specifically targets the BCR-ABL fusion protein produced by the Philadelphia chromosome abnormality, as well as other tyrosine kinases such as c-KIT and PDGFR. Imatinib Base is the free base form of imatinib, typically used in pharmaceutical manufacturing before conversion into its mesylate salt form. It is primarily indicated for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), and is also used in gastrointestinal stromal tumors (GISTs) and certain other rare malignancies driven by kinase mutations. Its development marked a breakthrough in targeted cancer therapy by offering a mechanism-based treatment with improved specificity compared to traditional chemotherapy.
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